Depending on the type and severity of your spasticity, injections of toxin may be used to treat symptoms such as movement disorder, hyperhidrosis, or spasticity. The effect of the toxin on muscles lasts between three and five months. The length of the toxin’s effect on the muscles depends on several factors such as the size of that muscle, how severe the spasticity is, and what type of treatment was used.
Spasticity treatment
Studies have shown that botulinumtoxin treatment of spasticity in cerebral palsy patients has positive results. The effectiveness of the treatment is dependent on many factors, such as muscle selection, age, along with accompanying therapy. Letibotulinum toxins A proved to be more effective than placebo in a phase III clinical trial. Secondary analyses examined the number and effectiveness of injections. Spasticity was defined as a change on the physician rating scale.
Botulinumtoxin injections generally begin to work within two weeks. The effect of one injection may last up to six months, although the effect wears off after a few months. It is possible to prolong the effects with multiple injections. In order to maximize the effect of botulinum, some patients will need to have occupational therapy as well as physical therapy.
Hyperhidrosis is treated
Local injections of Botulinum toxin type A have been shown to be an effective treatment for primary hyperhidrosis. These injections can be repeated for up to six months to see the desired effect. This treatment is cost-effective and affordable. This treatment is more effective than other options due to its safety and shorter recovery times.
Primary focal hyperhidrosis sufferers often find it difficult to get relief from their symptoms. Botulinum toxin A is injected under the skin to block the release of acetyl-choline, a neurotransmitter that mediates sympathetic neurotransmission in the sweat glands. The treatment with botulinum toxins A has proven successful in treating excessive sweating. This has resulted in a dramatic improvement of the patient's quality-of-life.
Treatment for movement disorder
Botulinumtoxin has recently been found to be beneficial in the treatment of patients with movement disorders. The treatment's effectiveness is dependent on the location and size of the affected muscles as well as the mode of administration. This article will discuss the effectiveness of the medication, its indications and the research that supports it.
Several types of movement disorders are treated with Botulinum toxin, including cervical dystonia, which involves overactive muscles in the neck, and generalized dystonia, which affects several muscle groups throughout the body. The treatment has been used to treat dyskinesias and motor fluctuations that are symptoms of young-onset Parkinson’s. The toxin can also be used for tremor, drooling, and constipation.
Botulinum Toxin Safety
Botulinumtoxin type A (Botox), a neurotoxin, inhibits acetylcholine formation by inhibiting the docking acetylcholine-vesicles at a cell membrane's inner surface. This prevents Acetylcholine (which is responsible for muscle contraction) from reaching neuromuscular joints. The result of this toxicity is a decrease in muscle tone.
Similar results were achieved using the Vancouver scar (VMS) as well as the visual analogue scales (VAS). The MD of the width of the scar was -1.06 (99.5%CI, -1.10 to -0.02). One botulinum-toxin treatment resulted in a 0-mm scarring. There was no difference between treatments. Although the new study's design is promising it will be necessary to continue research on different doses and variations between pre-surgical and after-surgical injection periods.